Computational and Experimental Protein Variant Interpretation



Kick Off Meeting

Project Acronym: CeProVI
Project Code: MIUR-PRIN-201744NR8S
Project Title: Integrative tools for defining the molecular basis of the diseases:
Computational and Experimental methods for Protein Variant Interpretation.


Meeting Schedule

WHEN: 11:00 AM - 2:00 PM, 5 September 2019
WHERE: FarBioMot Room - Department of Pharmacy and Biotecnology, Via Selmi 3, Bologna.


11:00 - 11:20
 
 
Piero Fariselli.
University of Torino (Unit 1).
The effect of variations on protein stability: problems and issues.
11:20 - 11:40
 
 
Emidio Capriotti and Paola Turina.
University of Bologna (Unit 2).
Methods for the automatic annotation of protein variants.
11:40 - 12:00
 
 
Roberta Chiaraluce and Valerio Consalvi.
University "La Sapienza" Roma (Unit 4).
Impact of nonsynonymous single nucleotide variants on protein fitness: experimental analysis for a comparative study.
12:00 - 12:20
 
 
Daniele Dell’Orco and Mariapina D'Onofrio
University of Verona (Unit 3).
Effects of point mutations on the stability and target-recognition in calcium sensor proteins.
12:20 - 12:40
 
 
Gaetano Salina, Silvia Morante and Giovanni La Penna
National Institute for Nuclear Physics (INFN) Roma (Unit 5).
Improving statistics in macromolecular interactions: agent-based models and atomistic simulations.
12:40 - 14:00
 
 
 
Open Discussion:
- Practical organization of the project: Tasks, deliverable and other activities.
- Budget remodulation: Remodeling of the deliverables and aims of the project.
- Future perspectives and goals: Organization of a research consumption and connections with international partners and enterprises.